diff --git a/patches/mfplat-MFStartup/definition b/patches/mfplat-MFStartup/definition
index 8ccd0840..fea895a3 100644
--- a/patches/mfplat-MFStartup/definition
+++ b/patches/mfplat-MFStartup/definition
@@ -1 +1,2 @@
-Fixes: [43607] Return S_OK from MFStartup stub
+# Fixes: [43607] Return S_OK from MFStartup stub
+Disabled: true
diff --git a/patches/patchinstall.sh b/patches/patchinstall.sh
index dcd183f8..05ebe12c 100755
--- a/patches/patchinstall.sh
+++ b/patches/patchinstall.sh
@@ -216,7 +216,6 @@ patch_enable_all ()
 	enable_libs_Unicode_Collation="$1"
 	enable_loader_OSX_Preloader="$1"
 	enable_makedep_PARENTSPEC="$1"
-	enable_mfplat_MFStartup="$1"
 	enable_mmsystem_dll16_MIDIHDR_Refcount="$1"
 	enable_mountmgr_DosDevices="$1"
 	enable_mpr_WNetGetUniversalNameW="$1"
@@ -925,9 +924,6 @@ patch_enable ()
 		makedep-PARENTSPEC)
 			enable_makedep_PARENTSPEC="$2"
 			;;
-		mfplat-MFStartup)
-			enable_mfplat_MFStartup="$2"
-			;;
 		mmsystem.dll16-MIDIHDR_Refcount)
 			enable_mmsystem_dll16_MIDIHDR_Refcount="$2"
 			;;
@@ -5638,21 +5634,6 @@ if test "$enable_makedep_PARENTSPEC" -eq 1; then
 	) >> "$patchlist"
 fi
 
-# Patchset mfplat-MFStartup
-# |
-# | This patchset fixes the following Wine bugs:
-# |   *	[#43607] Return S_OK from MFStartup stub
-# |
-# | Modified files:
-# |   *	dlls/mfplat/main.c, dlls/mfplat/tests/mfplat.c
-# |
-if test "$enable_mfplat_MFStartup" -eq 1; then
-	patch_apply mfplat-MFStartup/0001-mfplat-Return-S_OK-from-MFStartup-stub.patch
-	(
-		printf '%s\n' '+    { "Sebastian Lackner", "mfplat: Return S_OK from MFStartup stub.", 1 },';
-	) >> "$patchlist"
-fi
-
 # Patchset mmsystem.dll16-MIDIHDR_Refcount
 # |
 # | This patchset fixes the following Wine bugs: