diff --git a/patches/patchinstall.sh b/patches/patchinstall.sh
index 0828b44e..90575780 100755
--- a/patches/patchinstall.sh
+++ b/patches/patchinstall.sh
@@ -283,6 +283,7 @@ patch_enable_all ()
 	enable_ws2_32_APC_Performance="$1"
 	enable_ws2_32_Connect_Time="$1"
 	enable_ws2_32_getsockopt="$1"
+	enable_wscript_support_d_u_switches="$1"
 	enable_xactengine_initial="$1"
 	enable_xactengine3_7_Notification="$1"
 	enable_xactengine3_7_PrepareWave="$1"
@@ -895,6 +896,9 @@ patch_enable ()
 		ws2_32-getsockopt)
 			enable_ws2_32_getsockopt="$2"
 			;;
+		wscript-support-d-u-switches)
+			enable_wscript_support_d_u_switches="$2"
+			;;
 		xactengine-initial)
 			enable_xactengine_initial="$2"
 			;;
@@ -4243,6 +4247,18 @@ if test "$enable_ws2_32_getsockopt" -eq 1; then
 	patch_apply ws2_32-getsockopt/0001-ws2_32-Divide-values-returned-by-SO_RCVBUF-and-SO_SN.patch
 fi
 
+# Patchset wscript-support-d-u-switches
+# |
+# | This patchset fixes the following Wine bugs:
+# |   *	[#49905] wscript: return TRUE for /d and /u stub switches
+# |
+# | Modified files:
+# |   *	programs/wscript/main.c
+# |
+if test "$enable_wscript_support_d_u_switches" -eq 1; then
+	patch_apply wscript-support-d-u-switches/0001-wscript-return-TRUE-for-d-and-u-stub-switches.patch
+fi
+
 # Patchset xactengine-initial
 # |
 # | This patchset fixes the following Wine bugs:
diff --git a/patches/wscript-support-d-u-switches/0001-wscript-return-TRUE-for-d-and-u-stub-switches.patch b/patches/wscript-support-d-u-switches/0001-wscript-return-TRUE-for-d-and-u-stub-switches.patch
new file mode 100644
index 00000000..69bd9809
--- /dev/null
+++ b/patches/wscript-support-d-u-switches/0001-wscript-return-TRUE-for-d-and-u-stub-switches.patch
@@ -0,0 +1,33 @@
+From d68918425e249c5c218ee6f0c9418e2e2daf9931 Mon Sep 17 00:00:00 2001
+From: Dmitry Kislyuk <dimaki@rocketmail.com>
+Date: Wed, 28 Apr 2021 09:47:41 -0500
+Subject: [PATCH] wscript: return TRUE for /d and /u stub switches
+
+Patch by Robert Wilhelm from bug:
+https://bugs.winehq.org/show_bug.cgi?id=49905
+
+VbsEdit is able to execute scripts with this patch applied.
+
+Signed-off-by: Dmitry Kislyuk <dimaki@rocketmail.com>
+---
+ programs/wscript/main.c | 4 ++++
+ 1 file changed, 4 insertions(+)
+
+diff --git a/programs/wscript/main.c b/programs/wscript/main.c
+index a7005a9289c..6d6e8935149 100644
+--- a/programs/wscript/main.c
++++ b/programs/wscript/main.c
+@@ -393,6 +393,10 @@ static BOOL set_host_properties(const WCHAR *prop)
+         wshInteractive = VARIANT_FALSE;
+     else if(wcsicmp(prop, L"nologo") == 0)
+         WINE_FIXME("ignored %s switch\n", debugstr_w(L"nologo"));
++    else if(wcsicmp(prop, L"d") == 0)
++        WINE_FIXME("ignored %s switch\n", debugstr_w(L"d"));
++   else if(wcsicmp(prop, L"u") == 0)
++        WINE_FIXME("ignored %s switch\n", debugstr_w(L"u"));
+     else
+     {
+         WINE_FIXME("unsupported switch %s\n", debugstr_w(prop));
+-- 
+2.30.2
+
diff --git a/patches/wscript-support-d-u-switches/definition b/patches/wscript-support-d-u-switches/definition
new file mode 100644
index 00000000..8ae3cf62
--- /dev/null
+++ b/patches/wscript-support-d-u-switches/definition
@@ -0,0 +1 @@
+Fixes: [49905] wscript: return TRUE for /d and /u stub switches