diff --git a/layout/reftests/bugs/reftest.list b/layout/reftests/bugs/reftest.list
index 8667487ee09..8b28ccd272e 100644
--- a/layout/reftests/bugs/reftest.list
+++ b/layout/reftests/bugs/reftest.list
@@ -1659,7 +1659,7 @@ skip-if(B2G) == 641770-1.html 641770-1-ref.html
 == 641856-1.html 641856-1-ref.html
 == 645491-1.html 645491-1-ref.html
 == 645768-1.html 645768-1-ref.html
-== 650228-1.html 650228-1-ref.html
+fails-if(layersGPUAccelerated&&cocoaWidget) fails-if(Android) == 650228-1.html 650228-1-ref.html # Quartz alpha blending doesn't match GL alpha blending
 needs-focus == 652301-1a.html 652301-1-ref.html
 needs-focus == 652301-1b.html 652301-1-ref.html
 == 652775-1.html 652775-1-ref.html