diff --git a/pkg/sentry/platform/kvm/filters_amd64.go b/pkg/sentry/platform/kvm/filters_amd64.go
index 2bcdde655..2ff3d6ea3 100644
--- a/pkg/sentry/platform/kvm/filters_amd64.go
+++ b/pkg/sentry/platform/kvm/filters_amd64.go
@@ -49,3 +49,12 @@ func (k *KVM) archSyscallFilters() seccomp.SyscallRules {
 		},
 	})
 }
+
+// HottestSyscalls implements Platform.HottestSyscalls.
+func (*KVM) HottestSyscalls() []uintptr {
+	return []uintptr{
+		unix.SYS_FUTEX,
+		unix.SYS_IOCTL,
+		unix.SYS_RT_SIGRETURN,
+	}
+}
diff --git a/pkg/sentry/platform/kvm/filters_arm64.go b/pkg/sentry/platform/kvm/filters_arm64.go
index 20884f2dc..2fa875446 100644
--- a/pkg/sentry/platform/kvm/filters_arm64.go
+++ b/pkg/sentry/platform/kvm/filters_arm64.go
@@ -33,3 +33,8 @@ func (*KVM) archSyscallFilters() seccomp.SyscallRules {
 		},
 	})
 }
+
+// HottestSyscalls implements Platform.HottestSyscalls.
+func (*KVM) HottestSyscalls() []uintptr {
+	return nil
+}
diff --git a/pkg/sentry/platform/kvm/kvm.go b/pkg/sentry/platform/kvm/kvm.go
index e1d0218e9..d7dec72b1 100644
--- a/pkg/sentry/platform/kvm/kvm.go
+++ b/pkg/sentry/platform/kvm/kvm.go
@@ -69,8 +69,6 @@ type KVM struct {
 
 	platform.DoesOwnPageTables
 
-	platform.HottestSyscallsNotSpecified
-
 	// machine is the backing VM.
 	machine *machine
 }
diff --git a/pkg/sentry/platform/systrap/filters_amd64.go b/pkg/sentry/platform/systrap/filters_amd64.go
index 5a8366439..90a72aa9f 100644
--- a/pkg/sentry/platform/systrap/filters_amd64.go
+++ b/pkg/sentry/platform/systrap/filters_amd64.go
@@ -18,6 +18,7 @@
 package systrap
 
 import (
+	"golang.org/x/sys/unix"
 	"gvisor.dev/gvisor/pkg/seccomp"
 )
 
@@ -25,3 +26,11 @@ import (
 func (*Systrap) archSyscallFilters() seccomp.SyscallRules {
 	return seccomp.SyscallRules{}
 }
+
+// HottestSyscalls implements Platform.HottestSyscalls.
+func (*Systrap) HottestSyscalls() []uintptr {
+	return []uintptr{
+		unix.SYS_FUTEX,
+		unix.SYS_NANOSLEEP,
+	}
+}
diff --git a/pkg/sentry/platform/systrap/filters_arm64.go b/pkg/sentry/platform/systrap/filters_arm64.go
index a379d0fcb..64c80aa3f 100644
--- a/pkg/sentry/platform/systrap/filters_arm64.go
+++ b/pkg/sentry/platform/systrap/filters_arm64.go
@@ -40,3 +40,8 @@ func (*Systrap) archSyscallFilters() seccomp.SyscallRules {
 		},
 	})
 }
+
+// HottestSyscalls implements Platform.HottestSyscalls.
+func (*Systrap) HottestSyscalls() []uintptr {
+	return nil
+}
diff --git a/pkg/sentry/platform/systrap/systrap.go b/pkg/sentry/platform/systrap/systrap.go
index f1217602d..e5869845c 100644
--- a/pkg/sentry/platform/systrap/systrap.go
+++ b/pkg/sentry/platform/systrap/systrap.go
@@ -301,7 +301,6 @@ type Systrap struct {
 	platform.NoCPUPreemptionDetection
 	platform.UseHostGlobalMemoryBarrier
 	platform.DoesNotOwnPageTables
-	platform.HottestSyscallsNotSpecified
 
 	// memoryFile is used to create a stub sysmsg stack
 	// which is shared with the Sentry.
diff --git a/runsc/boot/filter/config_amd64.go b/runsc/boot/filter/config_amd64.go
index 447542ec1..963da5552 100644
--- a/runsc/boot/filter/config_amd64.go
+++ b/runsc/boot/filter/config_amd64.go
@@ -46,5 +46,11 @@ func archFstatAtSysNo() uintptr {
 }
 
 func archSpecificHotSyscalls() []uintptr {
-	return nil // TODO(b/298726675): Populate.
+	return []uintptr{
+		unix.SYS_NANOSLEEP,  // Used a bunch
+		unix.SYS_SENDMMSG,   // Used by network workloads
+		unix.SYS_FSTAT,      // Used for file I/O
+		unix.SYS_PPOLL,      // Used in general for I/O
+		unix.SYS_EPOLL_WAIT, // Same
+	}
 }