diff --git a/science/InsightToolkit501/Makefile b/science/InsightToolkit501/Makefile
index 36263cbac051..c0d01e1e31db 100644
--- a/science/InsightToolkit501/Makefile
+++ b/science/InsightToolkit501/Makefile
@@ -42,6 +42,7 @@ CMAKE_ARGS+=	-DBUILD_SHARED_LIBS:BOOL=ON \
 		-DModule_ITKIOMIC:BOOL=ON \
 		-DModule_ITKIOTransformMINC:BOOL=ON \
 		-DModule_ITKReview:BOOL=ON
+CMAKE_ON=	-PIE
 USE_LDCONFIG=	${PREFIX}/lib/InsightToolkit
 ITK_VER=	${PORTVERSION:R}
 PLIST_SUB+=	ITK_VER=${ITK_VER}