diff -Naur Python-2.7.9-orig/Lib/ctypes/__init__.py Python-2.7.9/Lib/ctypes/__init__.py --- Python-2.7.9-orig/Lib/ctypes/__init__.py 2014-12-10 18:59:33.000000000 +0300 +++ Python-2.7.9/Lib/ctypes/__init__.py 2014-12-11 13:51:26.439800000 +0300 @@ -445,7 +445,9 @@ cdll = LibraryLoader(CDLL) pydll = LibraryLoader(PyDLL) -if _os.name in ("nt", "ce"): +if _os.name == "nt" and _sys.version.find('GCC') >= 0: + pythonapi = PyDLL("libpython%d.%d.dll" % _sys.version_info[:2], None) +elif _os.name in ("nt", "ce"): pythonapi = PyDLL("python dll", None, _sys.dllhandle) elif _sys.platform == "cygwin": pythonapi = PyDLL("libpython%d.%d.dll" % _sys.version_info[:2])