diff --git a/pcsx2-qt/Settings/EmulationSettingsWidget.cpp b/pcsx2-qt/Settings/EmulationSettingsWidget.cpp
index 07396255e3..c8a8606dcb 100644
--- a/pcsx2-qt/Settings/EmulationSettingsWidget.cpp
+++ b/pcsx2-qt/Settings/EmulationSettingsWidget.cpp
@@ -112,7 +112,7 @@ EmulationSettingsWidget::EmulationSettingsWidget(SettingsWindow* settings_dialog
 	dialog()->registerWidgetHelp(m_ui.eeCycleRate, tr("EE Cycle Rate"), tr("100% (Normal Speed)"),
 		tr("Higher values may increase internal framerate in games, but will increase CPU requirements substantially. "
 		   "Lower values will reduce the CPU load allowing lightweight games to run full speed on weaker CPUs."));
-	dialog()->registerWidgetHelp(m_ui.eeCycleSkipping, tr("EE Cycle Skip"), tr("Disabled"),
+	dialog()->registerWidgetHelp(m_ui.eeCycleSkipping, tr("EE Cycle Skipping"), tr("Disabled"),
 		tr("Makes the emulated Emotion Engine skip cycles. "
 		   //: SOTC = Shadow of the Colossus. A game's title, should not be translated unless an official translation exists.
 		   "Helps a small subset of games like SOTC. Most of the time it's harmful to performance."));
diff --git a/pcsx2-qt/Settings/FolderSettingsWidget.cpp b/pcsx2-qt/Settings/FolderSettingsWidget.cpp
index b6c0860a66..c9a0fc4371 100644
--- a/pcsx2-qt/Settings/FolderSettingsWidget.cpp
+++ b/pcsx2-qt/Settings/FolderSettingsWidget.cpp
@@ -22,9 +22,9 @@ FolderSettingsWidget::FolderSettingsWidget(SettingsWindow* settings_dialog, QWid
 		"Folders", "SaveStates", Path::Combine(EmuFolders::DataRoot, "sstates"));
 	SettingWidgetBinder::BindWidgetToFolderSetting(sif, m_ui.videoDumpingDirectory, m_ui.videoDumpingDirectoryBrowse, m_ui.videoDumpingDirectoryOpen, m_ui.videoDumpingDirectoryReset,
 		"Folders", "Videos", Path::Combine(EmuFolders::DataRoot, "videos"));
-	dialog()->registerWidgetHelp(m_ui.organizeSnapshotsByGame, tr("Organize Snapshots by Game"), tr("Unchecked"),
+	dialog()->registerWidgetHelp(m_ui.organizeSnapshotsByGame, tr("Save Snapshots in Game-Specific Folders"), tr("Unchecked"),
 		tr("Saves snapshots to per-game subfolders instead of a shared folder."));
-	dialog()->registerWidgetHelp(m_ui.organizeVideoDumpByGame, tr("Organize Video Recordings by Game"), tr("Unchecked"),
+	dialog()->registerWidgetHelp(m_ui.organizeVideoDumpByGame, tr("Save Video Recordings in Game-Specific Folders"), tr("Unchecked"),
 		tr("Saves video recordings to per-game subfolders instead of a shared folder."));
 }
 
diff --git a/pcsx2-qt/Settings/FolderSettingsWidget.ui b/pcsx2-qt/Settings/FolderSettingsWidget.ui
index d96bfe8aa8..33105d9fcf 100644
--- a/pcsx2-qt/Settings/FolderSettingsWidget.ui
+++ b/pcsx2-qt/Settings/FolderSettingsWidget.ui
@@ -294,7 +294,7 @@
       <item row="4" column="0">
        <widget class="QCheckBox" name="organizeVideoDumpByGame">
         <property name="text">
-         <string>Save Video Recording in Game-Specific Folders</string>
+         <string>Save Video Recordings in Game-Specific Folders</string>
         </property>
        </widget>
       </item>
diff --git a/pcsx2-qt/Settings/GraphicsSettingsWidget.cpp b/pcsx2-qt/Settings/GraphicsSettingsWidget.cpp
index 14a094144c..455be1a21e 100644
--- a/pcsx2-qt/Settings/GraphicsSettingsWidget.cpp
+++ b/pcsx2-qt/Settings/GraphicsSettingsWidget.cpp
@@ -410,10 +410,10 @@ GraphicsSettingsWidget::GraphicsSettingsWidget(SettingsWindow* settings_dialog,
 
 	// Display tab
 	{
-		dialog()->registerWidgetHelp(m_display.widescreenPatches, tr("Enable Widescreen Patches"), tr("Unchecked"),
+		dialog()->registerWidgetHelp(m_display.widescreenPatches, tr("Apply Widescreen Patches"), tr("Unchecked"),
 			tr("Automatically loads and applies widescreen patches on game start. Can cause issues."));
 
-		dialog()->registerWidgetHelp(m_display.noInterlacingPatches, tr("Enable No-Interlacing Patches"), tr("Unchecked"),
+		dialog()->registerWidgetHelp(m_display.noInterlacingPatches, tr("Apply No-Interlacing Patches"), tr("Unchecked"),
 			tr("Automatically loads and applies no-interlacing patches on game start. Can cause issues."));
 
 		dialog()->registerWidgetHelp(m_display.disableInterlaceOffset, tr("Disable Interlace Offset"), tr("Unchecked"),
@@ -764,10 +764,10 @@ GraphicsSettingsWidget::GraphicsSettingsWidget(SettingsWindow* settings_dialog,
 		dialog()->registerWidgetHelp(m_advanced.extendedUpscales, tr("Extended Upscaling Multipliers"), tr("Unchecked"),
 			tr("Displays additional, very high upscaling multipliers dependent on GPU and driver capability."));
 
-		dialog()->registerWidgetHelp(m_advanced.useDebugDevice, tr("Enable Debug Device"), tr("Unchecked"),
+		dialog()->registerWidgetHelp(m_advanced.useDebugDevice, tr("Use Debug Device"), tr("Unchecked"),
 			tr("Enables API-level validation of graphics commands."));
 
-		dialog()->registerWidgetHelp(m_advanced.useDebugBlend, tr("Enable Debug Blend"), tr("Unchecked"),
+		dialog()->registerWidgetHelp(m_advanced.useDebugBlend, tr("Use Debug Blend"), tr("Unchecked"),
 			tr("Forces SW blending and disables several optimizations."));
 
 		dialog()->registerWidgetHelp(m_advanced.gsDownloadMode, tr("GS Download Mode"), tr("Accurate"),
diff --git a/pcsx2-qt/Settings/InterfaceSettingsWidget.cpp b/pcsx2-qt/Settings/InterfaceSettingsWidget.cpp
index 0524a7b4fb..bed99543dc 100644
--- a/pcsx2-qt/Settings/InterfaceSettingsWidget.cpp
+++ b/pcsx2-qt/Settings/InterfaceSettingsWidget.cpp
@@ -201,7 +201,7 @@ InterfaceSettingsWidget::InterfaceSettingsWidget(SettingsWindow* settings_dialog
 		tr("Unchecked"), tr("Pauses the emulator when a controller with bindings is disconnected."));
 	dialog()->registerWidgetHelp(m_ui.promptOnStateLoadSaveFailure, tr("Prompt On State Load/Save Failure"),
 		tr("Checked"), tr("Displays a modal dialog when a save state load/save operation fails."));
-	dialog()->registerWidgetHelp(m_ui.preferEnglishGameList, tr("Prefer English Titles"), tr("Unchecked"),
+	dialog()->registerWidgetHelp(m_ui.preferEnglishGameList, tr("Prefer English Game Titles"), tr("Unchecked"),
 		tr("For games with both a title in the game's native language and one in English, prefer the English title. Affects how game titles are displayed on the game list, window title and Discord Presence"));
 	dialog()->registerWidgetHelp(m_ui.startFullscreen, tr("Start Fullscreen"), tr("Unchecked"),
 		tr("Automatically switches to fullscreen mode when a game is started."));
@@ -228,7 +228,7 @@ InterfaceSettingsWidget::InterfaceSettingsWidget(SettingsWindow* settings_dialog
 		m_ui.disableWindowResizing, tr("Disable Window Resizing"), tr("Unchecked"),
 		tr("Prevents the main window from being resized."));
 	dialog()->registerWidgetHelp(
-		m_ui.startFullscreenUI, tr("Start Big Picture Mode"), tr("Unchecked"),
+		m_ui.startFullscreenUI, tr("Start In Big Picture Mode"), tr("Unchecked"),
 		tr("Automatically starts Big Picture Mode instead of the regular Qt interface when PCSX2 launches."));
 	dialog()->registerWidgetHelp(
 		m_ui.backgroundBrowse, tr("Game List Background"), tr("None"),
diff --git a/pcsx2-qt/Settings/InterfaceSettingsWidget.ui b/pcsx2-qt/Settings/InterfaceSettingsWidget.ui
index 5424efc5a4..6ddcc6332a 100644
--- a/pcsx2-qt/Settings/InterfaceSettingsWidget.ui
+++ b/pcsx2-qt/Settings/InterfaceSettingsWidget.ui
@@ -153,7 +153,7 @@
       <item row="3" column="0">
        <widget class="QCheckBox" name="startFullscreenUI">
         <property name="text">
-         <string>Start Big Picture UI</string>
+         <string>Start In Big Picture Mode</string>
         </property>
        </widget>
       </item>
diff --git a/pcsx2/GS/GS.cpp b/pcsx2/GS/GS.cpp
index 52c19b9eca..e320f17a3f 100644
--- a/pcsx2/GS/GS.cpp
+++ b/pcsx2/GS/GS.cpp
@@ -1305,12 +1305,12 @@ BEGIN_HOTKEY_LIST(g_gs_hotkeys){"Screenshot", TRANSLATE_NOOP("Hotkeys", "Graphic
 					return;
 
 				static constexpr std::array<const char*, static_cast<u8>(AccBlendLevel::MaxCount)> s_blending_option_names = {{
-					TRANSLATE_NOOP("Hotkeys", "Minimum"),
-					TRANSLATE_NOOP("Hotkeys", "Basic"),
-					TRANSLATE_NOOP("Hotkeys", "Medium"),
-					TRANSLATE_NOOP("Hotkeys", "High"),
-					TRANSLATE_NOOP("Hotkeys", "Full"),
-					TRANSLATE_NOOP("Hotkeys", "Maximum"),
+					TRANSLATE_NOOP("Hotkeys_BlendAcc", "Minimum"),
+					TRANSLATE_NOOP("Hotkeys_BlendAcc", "Basic"),
+					TRANSLATE_NOOP("Hotkeys_BlendAcc", "Medium"),
+					TRANSLATE_NOOP("Hotkeys_BlendAcc", "High"),
+					TRANSLATE_NOOP("Hotkeys_BlendAcc", "Full"),
+					TRANSLATE_NOOP("Hotkeys_BlendAcc", "Maximum"),
 				}};
 
 				const AccBlendLevel new_blend_mode = static_cast<AccBlendLevel>(
diff --git a/pcsx2/Hotkeys.cpp b/pcsx2/Hotkeys.cpp
index 341b72fbb1..eb37ae682c 100644
--- a/pcsx2/Hotkeys.cpp
+++ b/pcsx2/Hotkeys.cpp
@@ -49,7 +49,7 @@ static void HotkeyAdjustVolume(const s32 delta)
 	// Volume-adjusting hotkeys override mute toggle hotkey. EmuConfig.SPU2.OutputMuted overrides hotkeys.
 	if (!SPU2::SetOutputMuted(false))
 	{
-		Host::AddIconOSDMessage("VolumeChanged", ICON_FA_VOLUME_XMARK, TRANSLATE_STR("Hotkeys", "Volume: Muted in Settings"));
+		Host::AddIconOSDMessage("VolumeChanged", ICON_FA_VOLUME_XMARK, TRANSLATE_STR("Hotkeys_Volume", "Volume: Muted in Settings"));
 		return;
 	}
 
@@ -63,12 +63,12 @@ static void HotkeyAdjustVolume(const s32 delta)
 	if (new_volume > 0 && new_volume < maximum_volume)
 	{
 		Host::AddIconOSDMessage("VolumeChanged", new_volume < 100 ? ICON_FA_VOLUME_LOW : ICON_FA_VOLUME_HIGH,
-			fmt::format(TRANSLATE_FS("Hotkeys", "Volume: {} to {}%"), delta < 0 ? TRANSLATE_STR("Hotkeys", "Decreased") : TRANSLATE_STR("Hotkeys", "Increased"), new_volume));
+			fmt::format(TRANSLATE_FS("Hotkeys_Volume", "Volume: {} to {}%"), delta < 0 ? TRANSLATE_STR("Hotkeys_Volume", "Decreased") : TRANSLATE_STR("Hotkeys_Volume", "Increased"), new_volume));
 	}
 	else
 	{
 		Host::AddIconOSDMessage("VolumeChanged", delta < 0 ? ICON_FA_VOLUME_OFF : ICON_FA_VOLUME_HIGH,
-			fmt::format(TRANSLATE_FS("Hotkeys", "Volume: {} {}% Reached"), delta < 0 ? TRANSLATE_STR("Hotkeys", "Minimum") : TRANSLATE_STR("Hotkeys", "Maximum"), new_volume));
+			fmt::format(TRANSLATE_FS("Hotkeys_Volume", "Volume: {} {}% Reached"), delta < 0 ? TRANSLATE_STR("Hotkeys_Volume", "Minimum") : TRANSLATE_STR("Hotkeys_Volume", "Maximum"), new_volume));
 	}
 }
 
@@ -81,16 +81,16 @@ static void HotkeyToggleMute()
 	if (SPU2::SetOutputMuted(!SPU2::IsOutputMuted()))
 	{
 		if (SPU2::IsOutputMuted())
-			Host::AddIconOSDMessage("VolumeChanged", ICON_FA_VOLUME_XMARK, TRANSLATE_STR("Hotkeys", "Volume: Muted"));
+			Host::AddIconOSDMessage("VolumeChanged", ICON_FA_VOLUME_XMARK, TRANSLATE_STR("Hotkeys_Volume", "Volume: Muted"));
 		else
 		{
 			const u32 current_volume = SPU2::GetOutputVolume();
 			Host::AddIconOSDMessage("VolumeChanged", current_volume < 100 ? (current_volume == 0 ? ICON_FA_VOLUME_OFF : ICON_FA_VOLUME_LOW) : ICON_FA_VOLUME_HIGH,
-				fmt::format(TRANSLATE_FS("Hotkeys", "Volume: Unmuted to {}%"), current_volume));
+				fmt::format(TRANSLATE_FS("Hotkeys_Volume", "Volume: Unmuted to {}%"), current_volume));
 		}
 	}
 	else
-		Host::AddIconOSDMessage("VolumeChanged", ICON_FA_VOLUME_XMARK, TRANSLATE_STR("Hotkeys", "Volume: Muted in Settings"));
+		Host::AddIconOSDMessage("VolumeChanged", ICON_FA_VOLUME_XMARK, TRANSLATE_STR("Hotkeys_Volume", "Volume: Muted in Settings"));
 }
 
 static void HotkeyLoadStateSlot(s32 slot)